What is sysytemic lupus erythematosus? SLE abbreviated as systemic lupus erythematosus is a autoimmune disorder which involves multiple systems of the human body as the name itself suggest. The disease once triggered can lead to pre programmed cell death known as apoptosis. Simply speaking the body which is normally in a healthy individual is programmed to recognize the difference between the host cell and the pathogen by which the pathogens entering human body are killed but the host cells are not affected. But in case of SLE the property of our immune system to distinguish between the host and the pathogen is lost due to reason unknown and thus the immune complex is abnormally sensitized and attacks the hosts own body cells causing severe damage and inflammatory reaction(erythema) The exact causes or triggers are still not clear however hormonal involvement,environmental factors,genetics and certain drugs are known to precipitate the disease. IS IT A COMMON DISEASE CONDITION? SLE is a rare pathology affecting 20 to 70 per 100000 individuals.specially women and more commonly of child bearing ages are most common victims probably due to hormonal mechanism acting behind it. People of African Carribean and Chinese ethnicity are seen to have more involvement of the disease than in white people. How to identify it? The most common symptoms of Sle is a malar Rash or a red pigmen
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